About Robuvit® Lignum Quercus robur (French oak) extract
Oak trees from the forest of Massif Central highland region of France. It extracted using water, without solvent, pesticides & herbicides. Standardized to >40% polyphenols: roburins, vescalagin, castalagin, grandinin, vescalin. Roburins are converted to Urolithin A & Urolithin B (the actives) by our gut microbiota.
Robuvit has the potential of increasing mitochondrial renewal (mitophagy) via the metabolite urolithin A. Urolithin B, another of Robuvit's metabolites, has been shown to be a regulator of skeletal muscle mass, enhancing growth and differentiation of myotubes. In addition, Robuvit has the potential of decreasing oxidative stress. It was also shown to increase ribosomal protein expression as well as mitochondrial gene expression.